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KMID : 0648420100150020126
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Journal of Korean Society of Pediatric Endocrinology
2010 Volume.15 No. 2 p.126 ~ p.132
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Pelvic Ultrasonography Findings in Girls with Precocious Puberty
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Kang Hyun-Ju
Cho Kyoung-Soon
Park So-Hyun
Jung Min-Ho
Lim Gye-Yeon
Suh Byung-Kyu
Lee Byung-Churl
Nam Ji-Sun
Cho Won-Kyung
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Abstract
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Purpose: We analyzed pelvic ultrasonography (USG) findings in girls with central precocious puberty (CPP) and
assessed the role of uterine and ovarian measurements in discriminating between CPP and other pubertal conditions.
Methods: Seventy-four girls (chronological age 7.8 ± 0.5 years, bone age 9.9 ± 0.8 years) with precocious pubertal signs were enrolled. Measurements of uterine and ovarian parameters by pelvic USG included antero-posterior
diameters of the uterine fundus and cervix, diameter of each ovary, number of follicles, and maximal diameter of the largest follicle. The pelvic USG parameters were compared between girls with CPP (n = 49) and girls with atypical premature thelarche (PT) (n = 25).
Results: Antero-posterior diameter of uterine fundus (1.05 ± 0.34 vs. 0.74 ± 0.78 cm, P = 0.001), maximal ovarian
diameter (2.13 ± 0.48 vs. 1.84 ± 0.74 cm, P = 0.048) and mean ovarian area (2.31 ± 0.79 vs. 1.69 ± 0.71 cm, P =0.002) were significantly greater in girls with CPP than in girls with atypical PT. For the diagnosis of CPP, the sensitivity and specificity of A-P diameter of uterine fundus (? 0.9 cm) was 65.3% and 84.0%, the sensitivity and specificity of maximal ovarian diameter (? 2.0 cm) was 55.1% and 76%, and the sensitivity and specificity of mean ovarian area (? 2.0 cm2) was 62.9% and 80.0%.
Conclusion: Girls with CPP had significantly higher dimensions of the uterus and ovary measurements compared
to girls with atypical PT, but sensitivity and specificity were not high enough to differentiate CPP from atypical PT. Pelvic USG may help the diagnosis of CPP in girls.
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KEYWORD
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Puberty, precocious, Ultrasonography, P
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